A synthetic DNA walker for molecular transport.

نویسندگان

  • Jong-Shik Shin
  • Niles A Pierce
چکیده

Inspired by kinesin movement along a microtubule, we demonstrate a processive bipedal DNA walker. Powered by externally controlled DNA fuel strands, the walker locomotes with a 5 nm stride by advancing the trailing foot to the lead at each step. Real-time monitoring of specific bidirectional walker movement is achieved via multiplexed fluorescence quenching.

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عنوان ژورنال:
  • Journal of the American Chemical Society

دوره 126 35  شماره 

صفحات  -

تاریخ انتشار 2004